The diagram below shows a typical gas input schema for a global premier biologics manufacturer. As the organisms grow, mass flow needs within the reactor can scale radically, more so than in most chemical and industrial processes. The bioprocessing techniques required utilize unique control schemes, specific materials requirements and often complex gas control systems. The bioreactor environment poses some unique challenges to process and automation experts. This growth is carried out in a controlled environment typically termed a bioreactor or fermenter. Biologics, and Biosimilars, differ from conventional drugs in that they are grown in living cells, rather than manufactured using conventional chemical processes. An example of how to reduce cost and complexity for gas inputs utilizing high controllable range mass flow control.Īs the need for even more potent and specific pharmaceuticals grows, Pharma manufacturers have turned to Biologics to meet the increasing needs to solve complex and currently untreatable disease conditions (including cancer and myriad genetic diseases).
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